Experience with linezolid for the treatment of nocardiosis in organ transplant recipients.
Identifieur interne : 000507 ( Main/Exploration ); précédent : 000506; suivant : 000508Experience with linezolid for the treatment of nocardiosis in organ transplant recipients.
Auteurs : Oveimar De La Cruz [États-Unis] ; Lucio R. Minces [États-Unis] ; Fernanda P. Silveira [États-Unis]Source :
- The Journal of infection [ 1532-2742 ] ; 2015.
Descripteurs français
- KwdFr :
- Acétamides (pharmacologie), Adulte, Adulte d'âge moyen, Anti-infectieux (pharmacologie), Association triméthoprime-sulfaméthoxazole (pharmacologie), Femelle, Humains, Infections à Nocardia (diagnostic), Infections à Nocardia (traitement médicamenteux), Linézolide, Mâle, Nocardia (isolement et purification), Oxazolidinones (pharmacologie), Pennsylvanie, Résultat thérapeutique, Sujet âgé, Sujet âgé de 80 ans ou plus, Tests de sensibilité microbienne, Transplantation d'organe, Transplantation pulmonaire, Études rétrospectives.
- MESH :
- diagnostic : Infections à Nocardia.
- isolement et purification : Nocardia.
- pharmacologie : Acétamides, Anti-infectieux, Association triméthoprime-sulfaméthoxazole, Oxazolidinones.
- traitement médicamenteux : Infections à Nocardia.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Linézolide, Mâle, Pennsylvanie, Résultat thérapeutique, Sujet âgé, Sujet âgé de 80 ans ou plus, Tests de sensibilité microbienne, Transplantation d'organe, Transplantation pulmonaire, Études rétrospectives.
English descriptors
- KwdEn :
- Acetamides (pharmacology), Adult, Aged, Aged, 80 and over, Anti-Infective Agents (pharmacology), Female, Humans, Linezolid, Lung Transplantation, Male, Microbial Sensitivity Tests, Middle Aged, Nocardia (isolation & purification), Nocardia Infections (diagnosis), Nocardia Infections (drug therapy), Organ Transplantation, Oxazolidinones (pharmacology), Pennsylvania, Retrospective Studies, Treatment Outcome, Trimethoprim, Sulfamethoxazole Drug Combination (pharmacology).
- MESH :
- chemical , pharmacology : Acetamides, Anti-Infective Agents, Oxazolidinones, Trimethoprim, Sulfamethoxazole Drug Combination.
- geographic : Pennsylvania.
- diagnosis : Nocardia Infections.
- drug therapy : Nocardia Infections.
- isolation & purification : Nocardia.
- Adult, Aged, Aged, 80 and over, Female, Humans, Linezolid, Lung Transplantation, Male, Microbial Sensitivity Tests, Middle Aged, Organ Transplantation, Retrospective Studies, Treatment Outcome.
Abstract
Combination therapy with amikacin is recommended for treatment of nocardiosis in severely ill solid organ transplant recipients (SOT), but its use is complicated by nephrotoxicity. Linezolid has shown promise as an alternative in the empiric therapy of nocardiosis, but little is known about its effectiveness and safety in this setting. We describe the experience with linezolid for nocardiosis in SOT.
DOI: 10.1016/j.jinf.2014.08.010
PubMed: 25179664
Affiliations:
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Le document en format XML
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Linezolid has shown promise as an alternative in the empiric therapy of nocardiosis, but little is known about its effectiveness and safety in this setting. We describe the experience with linezolid for nocardiosis in SOT.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region></list><tree><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="De La Cruz, Oveimar" sort="De La Cruz, Oveimar" uniqKey="De La Cruz O" first="Oveimar" last="De La Cruz">Oveimar De La Cruz</name></region><name sortKey="Minces, Lucio R" sort="Minces, Lucio R" uniqKey="Minces L" first="Lucio R" last="Minces">Lucio R. Minces</name><name sortKey="Silveira, Fernanda P" sort="Silveira, Fernanda P" uniqKey="Silveira F" first="Fernanda P" last="Silveira">Fernanda P. Silveira</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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